Applications of nanoparticles for tissue and organ preservation application (Biotechnologie)

Beschreibung

Unter dem Titel Life Science Meets Engineering laden die Arbeitskreise der VDI Fachgesellschaft Technologies of Life Sciences gemeinsam jeweils an einem Mittwoch um 18 Uhr VDI-Mitglieder und interessierte Gäste zu spannenden Vorträgen mit anschließender Diskussion ein.

We have developed a scalable nanowarming technology for 1-80ml samples using radiofrequency-excited mesoporous silica coated iron oxide nanoparticles. Practical use of this technique in biological systems will be presented.

Cryopreservation and storage of biomaterials at low temperatures provides a potential revolution for tissue and organ recovery, allocation, and transplantation. However, in the case of larger tissues, cryoprotective solutions often fail due to damage caused by ice crystals. Thus, two technological barriers have to be overcome: (i) warming rates have to be high enough to avoid ice crystals, and (ii) re-warming has to be uniform throughout the tissue to avoid thermal stress. - This problems can be overcome by application of „nanowarming“. This technology uses iron oxide nanparticle heating physics.

In the presentation, state of the art of the technology will be described and examples for further application will discussed, including its potential in application for tumor tratment.

Der Referent: Dr. Navid Manuchehrabadi 

received a dual B.Sc. degree in Biomedical and Electric Ebgineering from Azad University, Teheran, Iran

He received a B.S. degree in Biomedical/Electrical Engineering, and M.S. in Biomedical and Mechanical Engineering from Leibniz Universitaet Hannover, Germany in 2009, He earned a Ph.D. degree in Mechanical Engineering from University of Maryland, Baltimore County (UMBC) in 2014.

Subsequent to his work as a post-doctoral fellow and a research assistant in the Department of Biomedical % Mechanical Engineering at the UMBC he worked as a R & D Research Engineer at Angio Dynamics, Marlborough, MA. Since March 2022 he is working as a research scientist at Biogen Inc., Cambridge, MA

Die Veranstaltung findet via ZOOM statt.